ქიმიის ტერმინთა განმარტებითი ლექსიკონი

A kinetic isotope effect that is attributable to isotopic substitution of an atom to which bonds are neither made nor broken in the rate-controlling step or in a pre-equilibrium step of a specified reaction, and is therefore not a primary isotope effect. One speaks of α, β, (etc.) secondary isotope effects, where α, β, (etc.) denote the position of isotopic substitution relative to the reaction centre. The corresponding isotope effect on the equilibrium constant of such a reaction is called a “secondary equilibrium isotope effect“.