The progress of mankind is due exclusively to the progress of natural sciences, not to morals, religion or philosophy.
Justus von Liebig, 1866
INVITED LECTURES
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Domino Reactions. Concepts for Efficient Organic Synthesis -
Synthesis of Mucin Glycopeptide Antigens for the Development of Antitumor Vaccines -
Organic and organometallic tectones for supramolecular gels -
Transition Metal-Catalyzed Allylic Alkylations – Versatile Tools for Amino Acid and Peptide Syntheses -
Synthesis of Carbocycles and Heterocycles via Cascade Reactions of Morita-Baylis-Hillman Adducts of Nitroalkenes -
Chemoselective Nucleophilic Addition to N-Alkoxyamides: Development and Application to the Total Synthesis of Gephyrotoxin -
D-galactal as a source of readily available benzopyrans, chromenes and chromans -
Riding the beast with a Smiles: a journey along isocyanide-based multicomponent reactions -
The three-center-four electron halogen bond -
Synthesis of novel peptides through multicomponent reactions and investigation of their biological activities -
The Tale of Two Enantiomers - Organic Synthesis of Inhibitors of Enzymes and Protein-Protein-Interactions -
Palladium-Catalyzed Cyclization of Propargylic Esters with Nucleophiles -
Novel Molecular Photosensitizers for Dye-Sensitized Solar Cells and Photodynamic Therapy Applications
| OUR HISTORY |
| OCS-2009 | GEOHET-2011 |
Prof. Horst Kunz
Professor emeritus of Organic and Bioorganic Chemistry
Address Institut fuer Organische Chemie
Johannes Gutenberg-Universitaet Mainz
Duesbergweg 10-14
D - 55099 Mainz, Germany,
e-mail: hokunz@uni-mainz.de
Date/Place of Birth:
December 3rd, 1940, Frankenhausen, Distr. Zwickau, Saxony, Germany
Academic Education
- 1961 Humboldt Universitaet, Berlin
- 1962 - 1969 Universitaet Mainz
Dr. rer. nat. (PhD)
1969 Thesis on organophosphorus chemistry (Supervisor Professor Leopold Horner), Universitaet Mainz
Habilitation
1977 "The alkaline hydrolysis of esters analogous to acetylcholine and its application in protecting group chemistry"
Academic Positions
- 1978 Associate Professor, Universitaet Mainz
- 1988 Full Professor (Chair) at Universitaet Mainz
Academic Distinctions
- 1992 Max-Bergmann-Medal
- 1995 Guest Professor, University Paris-Sud, Orsay, France
- 1995 Sandoz Foundation Lecture, Regensburg, Germany
- 1998 Member of the Saxony Academy of Science
- 1999 Novartis Lectureship in: Basel, Wien, Horsham, Summit
- 2000 Emil-Fischer-Medal
- 2001 Adolf-Windaus-Medal of the Universitaet Goettingen
Research Interests
Preparative Organic Chemistry, Natural Products, Carbohydrate Chemistry, Peptide Chemistry, Glycopeptide Synthesis, Stereoselective Synthesis, Combinatorial Chemistry.
Some Recent Publications
Stereoselective synthesis of enantiomerically pure nupharamine alkaloids from Castoreum
A. Stoye, G.Quandt, B. Brunnhöfer, E. Kapatsina, J. Baron, A. Fischer, M. Weymann, H. Kunz, Angew. Chem. 2009, 121, 2262-2264; Angew. Chem. Int. Ed. 2009, 48, 2228-2230.
A synthetic vaccine consisting of a tumor-associated Sialyl-Tn-MUC1 tandem repeat glycopeptide and Tetanus-Toxoid: induction of a strong highly selective immune response
A. Kaiser, N. Gaidzik, U. Westerlind, D. Kowalczyk, A. Hobel, E. Schmitt, H. Kunz, Angew. Chem. Int. Ed. 2009, 48, 7551-7555.
Synthetic antitumor vaccine containig MUC1 glycopeptides with two immundominant domains – induction of a strong immune response against breast tumor tissues
N. Gaidzik, A. Kaiser, D. Kowalczyk, U. Westerlind, B. Gerlitzki, H. P. Sinn, E. Schmitt, H. Kunz, Angew. Chem. 123 (2011), 10153-7; Angew. Chem. Int. Ed. 2011, 50,9977-9981.
The development of synthetic antitumor vaccines from mucin glycopeptide antigens. N. Gaidzik, U. Westerlind, H. Kunz, Chem. Soc. Rev. 2013, 42, 4421–4442
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